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Genostem members publications |
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Neotendon Formation Induced by Manipulation of the Smad8 Signaling Pathway in Mesenchymal Stem Cells GENOSTEM-funded collaboration between the Gazit group in Jerusalem and the Braunschweig group (WP5-tendon formation) has resulted in a study which has been recently accepted by the Journal of Clinical Investigation. The study demonstrates tendon formation in mesenchymal progenitors by the modification of a special signalling pathway initiated by BMPs (Smad8) and its application for regenerative therapies of tendon defect. Hoffmann, A., Pelled, G., Turgemann, G., Eberle, P., Zilberman,Y., Shinar, H., Keynan, K., Navon, G. Winkel, A., Gross, G. and Gazit, D. Neotendon Formation Induced by Manipulation of the Smad8 Signaling Pathway in Mesenchymal Stem Cells. J. Clinical Investigation, in press.
Regenerative Medicine - Special focus on Regenerative Medecine
A collection of review papers from several Genostem members has been recently published in the journal Regenerative Medecine , Vol 1 n°4 (http://www.futuremedicine.com) :
Tissue engineering through mesenchymal stem cells: role of the Genostem Consortium Christian Jorgensen Regenerative Medicine, July 2006, Vol. 1, No. 4, Pages 493-496.
The concept of mesenchymal stem cells Bruno Delorme, Sébastien Chateauvieux, Pierre Charbord Regenerative Medicine, July 2006, Vol. 1, No. 4, Pages 497-509.
Proteomics of primary mesenchymal stem cells S Roche, M Provansal, L Tiers, C Jorgensen, S Lehmann Regenerative Medicine, July 2006, Vol. 1, No. 4, Pages 511-517.
3D scaffolds for bone marrow stem cell support in bone repair Samer Srouji, Tali Kizhner, Erella Livne Regenerative Medicine, July 2006, Vol. 1, No. 4, Pages 519-528.
Engineered mesenchymal stem cells for cartilage repair Farida Djouad, Dominique Mrugala, Danièle Noël, Christian Jorgensen Regenerative Medicine, July 2006, Vol. 1, No. 4, Pages 529-537.
Osteogenic differentiation of human marrow-derived mesenchymal stem cells Pierre J Marie, Olivia Fromigué Regenerative Medicine, July 2006, Vol. 1, No. 4, Pages 539-548.
Applications of gene therapy and adult stem cells in bone bioengineering N Kimelman, G Pelled, Zul Gazit, D Gazit Regenerative Medicine, July 2006, Vol. 1, No. 4, Pages 549-561.
Tendon and ligament engineering: from cell biology to in vivo application Andrea Hoffmann, Gerhard Gross Regenerative Medicine, July 2006, Vol. 1, No. 4, Pages 563-574.
Engineering stem cells for therapy Marinela Mendez-Pertuz, Chris Hughes, Alex Annenkov, Gordon Daly, Yuti Chernajovsky Regenerative Medicine, July 2006, Vol. 1, No. 4, Pages 575-587.
Mesenchymal stem cells in bone and cartilage repair: current status Jean-Thomas Vilquin, Philippe Rosset Regenerative Medicine, July 2006, Vol. 1, No. 4, Pages 589-604.
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